Protein name:
Toll-like receptor 9 ;
Alternative:
CD:
CD289 ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with BTK and CNPY3 (By similarity). Interacts (via transmembrane domain) with UNC93B1.
Function:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type I membrane protein
Endosome
Lysosome
Cytoplasmic vesicle
phagosome
Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
Protein Attributes:
50:
MGPYCAPHPL | SLLVQAAALA | AALAEGTLPA | FLPCELQPHG | QVDCNWLFLK |
100:
SVPHFSAGAP | RANVTSLSLI | SNRIHHLHDS | DFVHLSNLRV | LNLKWNCPPA |
150:
GLSPMHFPCR | MTIEPNTFLA | VPTLEELNLS | YNGITTVPAL | PSSLVSLSLS |
200:
HTSILVLGPT | HFTGLHALRF | LYMDGNCYYM | NPCPRALEVA | PGALLGLGNL |
250:
THLSLKYNNL | TEVPRRLPPS | LDTLLLSYNH | IVTLAPEDLA | NLTALRVLDV |
300:
GGNCRRCDHA | RNPCRECPKN | FPKLHPDTFS | HLSRLEGLVL | KDSSLYKLEK |
350:
DWFRGLGRLQ | VLDLSENFLY | DYITKTTIFN | DLTQLRRLNL | SFNYHKKVSF |
400:
AHLHLASSFG | SLVSLEKLDM | HGIFFRSLTN | ITLQSLTRLP | KLQSLHLQLN |
450:
FINQAQLSIF | GAFPSLLFVD | LSDNRISGAA | TPAAALGEVD | SRVEVWRLPR |
500:
GLAPGPLDAV | SSKDFMPSCN | LNFTLDLSRN | NLVTIQQEMF | TRLSRLQCLR |
550:
LSHNSISQAV | NGSQFVPLTS | LRVLDLSHNK | LDLYHGRSFT | ELPQLEALDL |
600:
SYNSQPFSMQ | GVGHNLSFVA | QLPSLRYLSL | AHNGIHSRVS | QKLSSASLRA |
650:
LDFSGNSLSQ | MWAEGDLYLC | FFKGLRNLVQ | LDLSENHLHT | LLPRHLDNLP |
700:
KSLRQLRLRD | NNLAFFNWSS | LTVLPRLEAL | DLAGNQLKAL | SNGSLPPGIR |
750:
LQKLDVSSNS | IGFVIPGFFV | RATRLIELNL | SANALKTVDP | SWFGSLAGTL |
800:
KILDVSANPL | HCACGAAFVD | FLLERQEAVP | GLSRRVTCGS | PGQLQGRSIF |
850:
TQDLRLCLDE | TLSLDCFGLS | LLMVALGLAV | PMLHHLCGWD | LWYCFHLCLA |
900:
HLPRRRRQRG | EDTLLYDAVV | VFDKVQSAVA | DWVYNELRVQ | LEERRGRRAL |
950:
RLCLEERDWL | PGKTLFENLW | ASVYSSRKTM | FVLDHTDRVS | GLLRASFLLA |
1000:
QQRLLEDRKD | VVVLVILRPA | AYRSRYVRLR | QRLCRQSVLL | WPHQPSGQGS |
1029:
FWANLGIALT | RDNRHFYNRN | FCRGPTTAE
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Dog
Mouse
Bovine
ELISA Kit for Bovine Toll-like receptor 9
ELISA Kit for Bovine Toll-like receptor 9
ELISA Kit for Bovine Toll-like receptor 9
ELISA Kit for Bovine Toll-like receptor 9
ELISA Kit for Bovine Toll-like receptor 9
CLIA Kit for Bovine Toll-like receptor 9
CLIA Kit for Bovine Toll-like receptor 9
CLIA Kit for Bovine Toll-like receptor 9
CLIA Kit for Bovine Toll-like receptor 9
CLIA Kit for Bovine Toll-like receptor 9
Polyclonal Antibody for Bovine Toll-like receptor 9
Polyclonal Antibody for Bovine Toll-like receptor 9
Polyclonal Antibody for Bovine Toll-like receptor 9
Polyclonal Antibody for Bovine Toll-like receptor 9
Polyclonal Antibody for Bovine Toll-like receptor 9
Monoclonal Antibody for Bovine Toll-like receptor 9
Monoclonal Antibody for Bovine Toll-like receptor 9
Monoclonal Antibody for Bovine Toll-like receptor 9
Monoclonal Antibody for Bovine Toll-like receptor 9
Monoclonal Antibody for Bovine Toll-like receptor 9
Protein for Bovine Toll-like receptor 9
Protein for Bovine Toll-like receptor 9
Protein for Bovine Toll-like receptor 9
Protein for Bovine Toll-like receptor 9
Protein for Bovine Toll-like receptor 9
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Spleen .